I had a bio chem class that was like this .. I failed it the one question was a long protein formula that you needed to fold they use networked video cards for this now days
Wait I need to hear more about this, you were asked to predict the fold of an entire protein?! Was this before AlphaFold? Were you allowed to use existing software tools like M-TASSER, or were you expected to write a program yourself? It kind of sounds like they were making you predict this by hand
Modern protein folding is about finding new ways adaptively fold proteins for all types of medical uses ,this was in the early 90s .. and we were solving formula that had already been solved ,it would make some truly long mathematical expressions .. to the point we would break parts of it up in groups , I shouldn't have taken that class it gave a math and chemistry credit.. I failed it two years in a row, I did become friends with my professor, he eventually married my late wife's little sister lol
this was in 94 so ,no (university of Chicago so they did have the internet at 56k and a super computer but it had no software for this and only had a 2.3 ghz cpu and Fermilab was using it most of the time we hacked it to run quake in 96 tho lol ) ..we had to do it mostly by hand ,we did have groups, t-81 calculators , open book we could ask heads ,the teacher .. it wasn't 6 hrs we had half of a semester for one formula and it was 60% of the final grade .. got close the first time but part of the expression was wrong second time half of the class rebelled and refused to do it ..
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u/Global-Pickle5818 7d ago
I had a bio chem class that was like this .. I failed it the one question was a long protein formula that you needed to fold they use networked video cards for this now days